Stay Up to Date! Subscribe via email:

Enter your email address:

Delivered by FeedBurner

Wednesday, May 22, 2013

Major Cat Allergen levels in the home of patients with asthma and their relationship to sensitization to cat dander.


Introduction: Many studies have shown that dust mite and cat are the most common indoor allergies.
Allergies, in particular allergies to furry animals, increase the risk of chronic asthma and of emergency visits due to asthma attacks.

Cat allergy is very common, even for people who don’t own a cat. Previous studies have shown that cat allergen can be found in the carpets and mattresses of homes where cats are kept but also in homes where a cat has never been present.  

Research questions:
  • How much cat allergen can be found in the homes of asthmatic patients? 
  • How does having a cat affect the amount of allergen found?
  • Does the concentration of cat allergen in a home affect skin allergy tests to cats?
  • Does climate affect the amount of cat allergen found in a home?

What was done:  120 adults and children with asthma participated in the study. Participants lived in Winnipeg, Manitoba or in Vancouver, British Columbia.

Questionnaires: Participants answered questions about their asthma control, use of medication, smoking habits and asthma triggers.  They were also asked if there was a cat living in the home or if they frequently visited someone with a cat. 
Home visits: Each home was visited four times (once every season). Dust samples were collected from the bedrooms and the mattresses using a portable vacuum  cleaner and a special filter.
Skin testing: All participants were allergy tested to 11 different environmental allergens, including cats.  Skin testing was done at the beginning of the study.

Results:  90% of the children and 80% of the adults had allergies. Cat allergy was the most common allergy with 60% of the participants being allergic to cats.   Although only 15% of the homes had one or more cats, cat allergen was found in almost all (92%) of the homes. Homes with cats had the highest amount of cat allergen.
           
In Winnipeg, the amount of cat allergen found in homes without a cat was higher in winter and in spring.  In Vancouver, the amount of cat allergen in homes without a cat was the same all year round.

The amount of cat allergen was the same all year round in all homes that did have a cat.   

The incidence of cat allergy was the same for the participants that had a cat in the home as it was for participants that did not have a cat in the home.

The amount of cat allergen in the home did not seem to affect the risk of having a positive skin test to cats.

Conclusions: It is impossible to completely avoid cat allergen. A certain amount of cat allergen is present in almost all Canadian homes.

The amount of cat allergen in a home can be quite high, even if the home is cat-free. Indirect contact with a cat (visiting a friend with a cat) influences the amount of allergen found in a cat-free home. 

This may explain why so many people with asthma develop a cat allergy even if they have never had a cat.

Seasons only affect the amount of cat allergen in homes that DO NOT have a cat. High concentrations of cat allergen are present all year round if a cat lives in the home.

Having a cat free home does not seem to prevent the development of cat allergy but it does decrease the amount of cat allergen in the home. We still don’t know how much cat allergen is needed to develop a cat allergy or allergic symptoms. The amount needed to develop symptoms of asthma differs greatly from one person to another.

It is still very important for patients with asthma who are allergic to cats to minimize their exposure as much as possible.

 1995 Oct;75(4):325-30.Major cat allergen (Fel d I) levels in the homes of patients with asthma and their relationship to sensitization to cat dander. Quirce SDimich-Ward HChan HFerguson ABecker AManfreda JSimons EChan-Yeung M.

No comments:

Post a Comment